Village Medicine Seattle Treatment Highlight - Total Plasma Exchange

A Breakthrough Treatment at Village Medicine Seattle

Hello from Village Medicine, Seattle! I’m Dr. Paul Miszczyszyn, and I’m excited to share information about a cutting-edge therapy we offer called Total Plasma Exchange (TPE), also known as Therapeutic Plasma Exchange. This treatment has been life-changing for many of our patients with chronic conditions, and we’re thrilled to make it available to our community.

WHAT IS TPE? TOTAL PLASMA EXCHANGE

Imagine your blood as a river carrying essential nutrients, but also unwanted debris like inflammatory molecules. TPE, employing a process know as Plasmapheresis acts as a filtration system for this river.

During the treatment, your blood is gently drawn from one arm and circulated through a specialized device. This device separates the blood into its components, removing the plasma—the liquid portion containing the “debris.” This plasma is then replaced with a clean, sterile plasma solution, and the filtered blood is returned to your body through the other arm.

WHAT CONDITIONS WOULD BENEFIT?

TPE is an FDA-approved treatment for a variety of conditions where the immune system mistakenly attacks the body. Here are some of the conditions TPE can help with:

• Guillain-Barré syndrome (GBS): A neurological disorder where the immune system attacks the nerves.
• Chronic inflammatory demyelinating polyneuropathy (CIDP): A neurological disorder causing progressive weakness and impaired sensory function in the legs and arms.
• Myasthenia gravis (MG): A chronic autoimmune neuromuscular disease that causes weakness in the skeletal muscles.
• Lambert-Eaton myasthenic syndrome (LEMS): An autoimmune disease that affects the connection between nerves and muscles.
• Kidney diseases: Certain kidney diseases like lupus nephritis or Goodpasture syndrome.

Case Study: TPE is an emerging treatment modality in patients suffering both neurologic and non-neurologic diseases

HOW CAN TPE HELP YOU?

By removing harmful antibodies and inflammatory factors, TPE can help:

• Reduce symptoms like pain, fatigue, and weakness
• Slow the progression of your disease
• Improve your overall quality of life

WHY CHOOSE VILLAGE MEDICINE FOR TPE?

At Village Medicine, we take an integrative approach to your health. We combine the latest medical advancements like TPE with personalized care and a focus on your overall well-being. Our experienced team is dedicated to providing you with the highest quality care in a comfortable and supportive environment.

READY TO LEARN MORE?

If you think TPE might be right for you, or if you simply want to learn more, please don’t hesitate to contact us at Village Medicine. We’re happy to answer your questions and schedule a consultation

* This post was originally printed in the Village Medicine Seattle’s Wellness Quarterly Magazine, 2Q25 Edition. Read and download the full publication

About The Author

Dr. Paul Miszczyszyn, ND is a Naturopathic Physician, IV Medicine & Regenerative Injection specialist with Village Medicine Seattle. Paul believes that our biomedical health reverberates into every part of our lives: work, relationships, physicality, and attitude. Learn more about Dr. Paul